Stay Safe: Hexadecyltrimethylammonium Bromide msds

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  • Product Namely: Hexadecyltrimethylammonium bromide.
  • Signal Sign: Danger!
  • Vital Info: Hexadecyltrimethylammonium Bromide msds – Stay Safe!

A popular cationic surfactant used as a detergent, emulsifier, and reagent in numerous chemical processes is hexadecyltrimethylammonium bromide (CTAB). It is a powder that can be white or off-white and dissolves in both ethanol and water.


  • Acute toxicity, Oral: If consumed, harmful.
  • It causes skin irritation
  • It causes serious eye damage.
  • May irritate the respiratory tract.
  • If eaten, prolonged or repeated exposure could harm internal organs (gastrointestinal tract).
  • extremely harmful to aquatic life and has long-term consequences.


  • Name of Component: N-Cetyl-N’N’N-trimethylammonium bromide.
  • Synonyms: Cetrimonium bromide, Palmityltrimethylammonium bromide, CTAB, and Cetyltrimethylammonium bromide.
  • Formula: C19H42N.Br
  • Molecular weight: 364,45 g/mol.
  • CAS-No. : 57-09-0.
  • EC-No. : 200-311-3.


  • If you feel unwell, contact a doctor.
  • If inhaled: Remove the victim to fresh air & keep them at rest in a breathing-friendly position.
  • If in the eyes: Carefully rinse for a few minutes(20 minutes) with water. If contact lenses are present & simply possible to remove, do so. Rinsing continues.
  • If in the eyes irritation persists: Contact an ophthalmologist(eye doctor).
  • If swallowed: After swallowing, make the person drink water right after (two glasses at most). Consult a doctor.


  • Appropriate Extinguishing Substances: Use carbon dioxide, alcohol-resistant foam, dry chemicals, or water spray.

Particular risks associated with the substance or mixture:

  • Oxides of carbon.
  • Oxides of nitrogen (NOx).
  • Gaseous hydrogen bromide.
  • Combustible.
  • Because they are heavier than air, vapors can move across floors.
  • With extreme heating produces explosive mixtures with air.
  • In the event of a fire, it is possible for harmful combustion gases or vapors to develop.


  • Restrict access to the area for unprotected individuals.
  • Block solid from becoming airborne.
  • The spill should be swept up, put in a sealed bag or container, & thrown away.
  • After the stuff has been picked up, clean the spill area.
  • Do not allow stuff to go down the drain.
  • Air out the area.


  • Keep the container firmly shut.
  • Place it in a dry place.
  • Class of Storage: Combustible solids.


  • Wear safety gear(PPE), including gloves, clothes, & eye protection.
  • After handling, carefully wash your hands.
  • Environmental Exposure Control: Do not allow stuff to go down drains.


  • Chemical nature: Cationic surfactant.
  • Form(appearance): White or off-white powder(crystalline).
  • Color: White to off-white.
  • Odor: Mild, characteristic, weak.
  • Melting point/range: 248 – 251°C.
  • Initial boiling point & boiling range: No data available.
  • Flammability (solid, gas): No data available.
  • Upper/lower flammability or explosive limits: No data available.
  • Flashpoint: 244°C – closed cup.
  • Autoignition Temperature: 210°C at 0,3 hPa.
  • pH: 5.0 – 7 at 36,4 g/l at 25°C.
  • Viscosity(kinematic/dynamic): No data available.
  • Partition coefficient(n-octanol/water): log Pow: 2,26 – (Lit.), Bioaccumulation is not expected.
  • Vapor pressure: No data available.
  • Density: 2.30 g/cm3.
  • Relative density: No data available.
  • Relative vapor density: No data available.
  • Particle characteristics: No data available.
  • Explosive properties: No data available.
  • Oxidizing properties: Nil.
  • Surface tension: 39 mN/m at 25°C.


  • Reactivity: When heated intensely, produces explosive combinations with air & range from approx. 15 Kelvin below the flash point is to be rated as crucial.
  • Chemical Stability: Under typical environmental circumstances, the product is chemically stable (room temperature).
  • Hazardous/Violent Reactions: Avoid strong oxidizing agents.
  • Safety: Nitrosamines may be released when in contact with nitrites, nitrates, or nitrous acid.
  • Avoiding Condition: Strong heating should be avoided.


  • Acute Toxicity: 
LD50 Oral-Rat-female-1.550 mg/kg
(OECD Test Guideline 401)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: Hexadecyltrimethylammonium
Inhalation: No data available
LD50 Dermal-Rabbit-male & female-2.150 mg/kg
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: Hexadecyltrimethylammonium
  • Skin corrosion/irritation:
Result: Irritating to skin.-24 h
  • Serious eye damage/eye irritation:
Result: It causes serious eye damage.
(OECD Test – Guideline 405)
Remarks: in analogy to similar products.
  • Respiratory or skin sensitization:
Maximization Test-Guinea pig.
Result: Negative
(OECD Test Guideline 406)
Remarks: Aqueous solution.
  • Germ cell mutagenicity: No data available.
  • Carcinogenicity: Unavailable data.
  • Reproductive Toxicity: Unavailable data.
  • Single exposure, specific target organ Toxicity: Inhalation-This may irritate the respiratory tract or breathing system.
  • Specific target organ toxicity-repeated exposure: Oral – Prolonged or repeated exposure to this substance may harm internal organs. gastrointestinal system.
  • Aspiration hazard: No data available.
  • We believe that there hasn’t been enough research done on the chemical, physical, and toxicological aspects.


  • Toxicity to fish: semi-static test LC50 – Danio rerio (zebra fish) – 0,2 mg/l – 96 h (OECD Test Guideline 203).
  • Toxicity to daphnia & other aquatic invertebrates: semi-static test EC50 – Daphnia magna (Water flea) – 0,037 mg/l – 48 h (OECD Test Guideline 202).
  • Toxicity to algae:
  1. Static test ErC50 – Pseudokirchneriella subcapitata (green algae) – 0,00411 mg/l – 72 h (OECD Test Guideline 201)
  2. Static test NOEC – Desmodesmus subspicatus (green algae) – 0,001 mg/l – 72 h (OECD Test Guideline 201).
  • Toxicity to bacteria: EC50 – activated sludge – 19 mg/l; Remarks: (ECHA).
  • Persistence & degradability(Biodegradability): Aerobic Chemical oxygen demand-Exposure time 11 d; Result: 100 % – Readily biodegradable(OECD Test Guideline 301E).
  • Bioaccumulative potential(Bioaccumulation): Cyprinus carpio (Carp)-8 Weeks-0,05 mg/l(N-Cetyl-N’N’N-trimethylammonium bromide).

Accumulation in living organisms is not anticipated because of the distribution coefficient of n-octanol/water.

  • Mobility in soil: No data available.
  • Results of PBT and vPvB assessment: There are no components in this substance/mixture that are persistent, bioaccumulative, or toxic (PBT) or very persistent & very bioaccumulative (vPvB) at concentrations of 0.1% or more.
  • It is very toxic to aquatic life.
  • Endocrine-disrupting properties: There are no ingredients in the substance or mixture that are thought to have endocrine-disrupting qualities(Commission Regulation (EU) 2018/605 at levels of 0.1% or higher).


  • Dispose of in accordance with local, state, & federal rules or laws.


  • UN Proper Name of Shipping: According to (ADR/RID/IMDG/IATA:3077), Environmentally hazardous substance, solid, n.o.s. (N-Cetyl-N’N’Ntrimethylammonium bromide).


  • This material safety data sheet conforms with Regulation (EC) No. 1907/2006’s criteria.
  • For this product, a chemical safety assessment wasn’t carried out.


This Hexadecyltrimethylammonium Bromide msds is intended as a compendium & is based on data & tests that are likely to be reliable. I don’t guarantee the data’s correctness or completeness & I’m not responsible for any resulting losses. The information is only being provided for your review, research, & verification. I DO NOT ASSUME RESPONSIBILITY AND EXPRESSLY DISCLAIM LIABILITY FOR LOSS, DAMAGE, OR EXPENSE RESULTING FROM OR IN ANY WAY CONNECTED WITH THE HANDLING, STORAGE, USE, OR DISPOSAL OF THIS PRODUCT FOR THE FOREGOING AND OTHER REASONS.
Hexadecyltrimethylammonium Bromide msds
Hexadecyltrimethylammonium Bromide


Read out this, Hexadecyltrimethylammonium Bromide msds because Inappropriate handling of the cationic surfactant hexadecyltrimethylammonium bromide (CTAB) can result in respiratory discomfort, moderate skin irritation or allergic responses, stomach distress, nausea, vomiting, or diarrhea. It should be stored in a cool, dry, well-ventilated environment, away from heat and ignition sources, and handled with the proper personal protective equipment and ventilation. In the event of a spill or leak, the correct steps should be taken to remove the substance and safely dispose of it. Although CTAB is frequently used as a detergent, an emulsifier, and a reagent in a variety of chemical reactions, it should only be used under the supervision of a qualified professional, handled with the appropriate training & safety precautions, and in accordance with all applicable laws & standards.

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